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Grant Award View - GA30035

Inhibition of PRMT5 as a cancer therapy

Contact Details

NHMRC Research Help Centre

:
1800 500 983

:

GA ID:
GA30035
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
21-Dec-2018
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2023
Value (AUD):
$1,527,367.50 (GST inclusive where applicable)

One-off/Ad hoc:
No
Aggregate Grant Award:
No

PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Inhibition of PRMT5 as a cancer therapy
Purpose:

This proposal is aimed at improving the clinical benefit of BRAF/MEK and CDK4 inhibitors by combining with PRMT5 inhibition and extending these combination therapies into cancers with poor outcomes (pancreatic and oesophageal). These studies will provide mechanistic insight into the action of PRMT5 inhibitors in RAS/RAF/CDK4 driven tumours and identify patients that will likely benefit from PRMT5 therapy including combination therapy.


GO ID:
GO Title:
NHMRC Project Grant Scheme
Internal Reference ID:
GNT1158190
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property

Grant Recipient Details

Recipient Name:
University of Melbourne
Recipient ABN:
84 002 705 224

Grant Recipient Location

Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
VIC
Postcode:
Country:
AUSTRALIA

Contact Details

NHMRC Research Help Centre

:
1800 500 983

: