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Grant Award View - GA268448
Pre-clinical evaluation of selective adenosine A1 receptor positive...
GA ID:
GA268448
Agency:
Department of Health and Aged Care
Approval Date:
17-Jun-2022
Publish Date:
4-Oct-2022
Category:
Medical Research
Grant Term:
17-Jun-2022 to 31-May-2027
Value (AUD):
$3,849,003.60
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
DoHAC 21/22 1.1 Health Policy Research and Analysis
Grant Program:
MRFF Research Grants
Grant Activity:
Pre-clinical evaluation of selective adenosine A1 receptor positive allosteric modulators for the treatment of drug-resistant epilepsy
Purpose:
Current drugs for epilepsy have limited efficacy because of over-reliance on a few animal models of provoked seizures to randomly screen compounds in preclinical development, resulting in many ‘me-too’ drugs that have limited modes of actions. This project will utilise our stem cell derived neural and heart platforms to develop a brand new class of compounds and test them in an animal model of drug-resistant epilepsy. Upon project completion the compounds will be ready for clinical trialling.
GO ID:
GO Title:
MRFF – Stem Cell Therapies Mission – 2021 Stem Cell Therapies Grant Opportunity
Internal Reference ID:
2022/MRF2015957
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
Country:
AUSTRALIA