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Grant Award View - GA29856
Targeting the TWEAK/Fn14 signalling pathway as a novel therapeutic...
GA ID:
GA29856
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
21-Dec-2018
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2022
Value (AUD):
$997,485.80
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Targeting the TWEAK/Fn14 signalling pathway as a novel therapeutic strategy to prevent chronic liver disease progression.
Purpose:
TWEAK/Fn14 signalling critically regulates inflammation, fibrosis and liver progenitor cell responses - all processes involved in progressive chronic liver injury. In this study, we will now define the involved cell populations, identify the underlying mechanisms and test pharmacological targeting of this pathway as a novel therapeutic avenue to inhibit chronic liver disease progression to cancer. Importantly, we will also assess translatability of our findings into the human setting.
GO ID:
GO Title:
NHMRC Project Grant Scheme
Internal Reference ID:
GNT1160323
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Curtin University
Recipient ABN:
99 143 842 569
Grant Recipient Location
Suburb:
Bentley
Town/City:
Bentley
Postcode:
6102
State/Territory:
WA
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
WA, QLD, Overseas
Postcode:
Multiple
Country:
AUSTRALIA, UNITED KINGDOM