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Grant Award View - GA29800
Deciphering the mechanisms of caspase-2-mediated suppression of...
GA ID:
GA29800
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
21-Dec-2018
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2021
Value (AUD):
$422,127.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Deciphering the mechanisms of caspase-2-mediated suppression of aneuploidy and tumourigenesis
Purpose:
Abnormal chromosome numbers (aneuploidy) is a feature of cancer cells. The extent of aneuploidy is often predictive of prognosis and treatment effectiveness. We have discovered that an enzyme, caspase-2, is important for selectively removing aneuploid cells. This study will identify and define the mechanisms and proteins that control caspase-2 to prevent aneuploidy to better understand how cancer cells can survive and be targeted for treatment.
GO ID:
GO Title:
NHMRC Project Grant Scheme
Internal Reference ID:
GNT1156601
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of South Australia
Recipient ABN:
37 191 313 308
Grant Recipient Location
Suburb:
Mawson Lake
Town/City:
Mawson Lake
Postcode:
5095
State/Territory:
SA
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC, SA
Postcode:
Multiple
Country:
AUSTRALIA