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Grant Award View - GA142269
Structural and functional studies of Helicobacter pylori flagellar motor
GA ID:
GA142269
Agency:
Australian Research Council
Approval Date:
11-Dec-2020
Publish Date:
15-Dec-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
8-Nov-2021 to 7-Nov-2024
Original: 1-Jan-2021 to 31-Dec-2023
Value (AUD):
$564,750.00
(GST inclusive where applicable)
Variations:
- GA142269-V3 - Variation to Grant (27-Jul-2022 )
- GA142269-V2 - Variation to Grant (20-Oct-2021 )
- GA142269-V1 - Variation to Grant (2-Aug-2021 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 20/21 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Structural and functional studies of Helicobacter pylori flagellar motor
Purpose:
This project investigates the bacterial flagellar motor specialised for locomotion in viscous fluids. Its striking feature, revealed by cryo-tomography, is a complex cage-like protein scaffold that is hypothesised to stabilise the wider force-generating ring of the motor to sustain a larger turning force. The aim is to unravel the make-up of this scaffold and the structural basis for its ability to recruit more force-generating units, in order to advance our fundamental knowledge about the mechanism of the bacterial flagellar motor, and about strategies used by nature to increase its performance under high viscosity conditions. This research is expected to add a new paradigm for how polar flagellar motors assemble and function in bacteria.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2021
Internal Reference ID:
DP21 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
MULGRAVE
Town/City:
MULGRAVE
Postcode:
3170
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3170
Country:
AUSTRALIA