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Grant Award View - GA142198-V1
Understanding telomere privilege in pluripotent stem cells
GA ID:
GA142198-V1
Agency:
Australian Research Council
Approval Date:
11-Dec-2020
Variation Publish Date:
2-Aug-2021
Variation Date:
27-Jul-2021
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jan-2021 to 31-Dec-2023
Value (AUD):
$611,481.20
(GST inclusive where applicable)
Varies:
GA142198
- Understanding telomere privilege in pluripotent stem cells
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 20/21 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Understanding telomere privilege in pluripotent stem cells
Purpose:
We recently identified that fundamental mechanisms which protect chromosome ends (i.e. “telomeresâ€) are not conserved between somatic and embryo-derived stem cells. This discovery is without precedent and challenges the dogmatic expectation that cellular functions promoting genome stability are conserved in stem cells. We term the unexpected protective capacity of pluripotent chromosome ends “telomere privilegeâ€. Here we will uncover the molecular, genomic, and proteomic regulators or telomere privilege; determine the breath of telomere privilege in stem cell lineages; elucidate the functional significance of telomere privilege; and exploit telomere privilege to study fundamental biology related to telomeres and the DNA damage response.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2021
Internal Reference ID:
DP21 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
FOREST LODGE
Town/City:
FOREST LODGE
Postcode:
2037
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2037
Country:
AUSTRALIA