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Grant Award View - GA279556
Functional impact of CTCF binding site mutations in 3D cancer genome...
GA ID:
GA279556
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
27-Oct-2022
Publish Date:
23-Jan-2023
Category:
Medical Research
Grant Term:
1-Jan-2023 to 31-Dec-2025
Value (AUD):
$978,137.74
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 21/22 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
Functional impact of CTCF binding site mutations in 3D cancer genome regulation
Purpose:
Understanding what regulates gene expression in normal cells and how this goes wrong in cancer is still one of the biggest challenges in modern biology. This grant is focused on investigating two classes of non-coding somatic mutations in breast and prostate cancer, which we hypothesise disrupt binding of an important DNA regulator (CTCF) and results in deregulation of specific regions of gene expression. Unravelling mechanisms underpinning CTCF site mutations may lead to new cancer treatments.
GO ID:
GO Title:
Ideas Grants 2022
Internal Reference ID:
2022/GNT2020334
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of New South Wales
Recipient ABN:
57 195 873 179
Grant Recipient Location
Suburb:
Kensington
Town/City:
Kensington
Postcode:
2052
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, NSW
Postcode:
Multiple
Country:
AUSTRALIA