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Grant Award View - GA352245
Improving durability of treatment for haemophilia A
GA ID:
GA352245
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
24-Aug-2023
Publish Date:
8-Jan-2024
Category:
Medical Research
Grant Term:
1-Jan-2024 to 31-Dec-2028
Value (AUD):
$2,954,040.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 22/23 1.1 Health and Medical Research
Grant Program:
Investigator Grants
Grant Activity:
Improving durability of treatment for haemophilia A
Purpose:
Haemophilia A affects 1 in 5000 males and is due to dysfunctional clotting factor FVIII that results in significant morbidity and increased mortality. Treatment with replacement FVIII does not work in one third of patients due to production of neutralising antibodies. FVIII gene therapy is showing promise, however expression of FVIII kills the transfected cells. This project is based on a new discovery about FVIII that may be exploited to overcome these roadblocks with current therapies.
GO ID:
GO Title:
Investigator Grants 2023
Internal Reference ID:
2023/GNT2026631
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
Camperdown
Town/City:
Camperdown
Postcode:
2050
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
Country:
AUSTRALIA