To access this element change to forms mode OFF
Grant Award View - GA28462-V1
Cysteamine dioxygenases: novel oxygen sensors implicated in hypoxia?
GA ID:
GA28462-V1
Agency:
Australian Research Council
Approval Date:
27-Nov-2018
Variation Publish Date:
13-Feb-2019
Variation Date:
1-May-2019
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-May-2019 to 30-Apr-2022
Value (AUD):
$422,574.00
(GST inclusive where applicable)
Varies:
GA28462
- Cysteamine dioxygenases: novel oxygen sensors implicated in hypoxia?
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 18/19 Discovery
Grant Program:
Discovery Early Career Researcher Award
Grant Activity:
Cysteamine dioxygenases: novel oxygen sensors implicated in hypoxia?
Purpose:
This project aims to characterise and manipulate a novel oxygen sensing system, the cysteamine dioxygenases, to help understand how mammalian cells respond to low oxygen concentrations, a condition known as hypoxia. A number of the world’s most destructive diseases can impair oxygen delivery, altering biochemical landscapes. By understanding how cells respond to fluctuations in oxygen, the project expects to develop effective methods to treat these detrimental conditions. Characterisation of the cysteamine dioxygenases could establish a novel mechanism by which cells monitor changes in oxygen, assisting in understanding hypoxia and disease. The project will also enable new cysteine initiating substrates to be identified, allowing the full impact of this regulatory process to be appreciated in mammals.
GO ID:
GO Title:
Discovery Early Career Researcher Award commencing in 2019
Internal Reference ID:
DE19 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
FOREST LODGE
Town/City:
FOREST LODGE
Postcode:
2037
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2037
Country:
AUSTRALIA