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Grant Award View - GA1983-V1
Stronger together: understanding antibiotic synergy on a molecular level
GA ID:
GA1983-V1
Agency:
Australian Research Council
Approval Date:
10-Nov-2017
Variation Publish Date:
20-Feb-2018
Variation Date:
3-Dec-2018
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
3-Dec-2018 to 2-Dec-2021
Value (AUD):
$365,058.00
(GST inclusive where applicable)
Varies:
GA1983
- Stronger together: understanding antibiotic synergy on a molecular level
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 17/18 Discovery
Grant Program:
Discovery Early Career Researcher Award
Grant Activity:
Stronger together: understanding antibiotic synergy on a molecular level
Purpose:
This project aims to use genomics-based approaches to answer fundamental questions about how antibiotic synergy works. Antibiotic combination therapy presents an opportunity to revive the use of antibiotics in otherwise resistant bacteria, yet currently there is little understanding of the molecular mechanisms underlying antibiotic synergy. Studies indicate that additional mechanisms of action (MOA) occur during synergistic killing beyond those of the original antibiotics. This project will identify genes involved in multiple synergistic treatments and determine how bacterial cells gain resistance. The synergy-specific MOA identified also represent an untapped reservoir of primary drug targets.
Internal Reference ID:
DE18 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Macquarie University
Recipient ABN:
90 952 801 237
Grant Recipient Location
Suburb:
MACQUARIE UNIVERSITY
Town/City:
MACQUARIE UNIVERSITY
Postcode:
2109
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2109
Country:
AUSTRALIA