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Grant Award View - GA1983

Stronger together: understanding antibiotic synergy on a molecular level

Contact Details

ARC NCGP General Enquiries

Phone:
02 6281 6600

Email Address:

GA ID:
GA1983
Agency:
Australian Research Council
Approval Date:
10-Nov-2017
Publish Date:
20-Feb-2018
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
3-Dec-2018 to 2-Dec-2021
Original: 1-Jan-2018 to 31-Dec-2020
Value (AUD):
$365,058.00 (GST inclusive where applicable)
Variations:
  • GA1983-V1 - Variation to Grant (20-Feb-2018 )

Ad hoc/One-off:
No
Aggregate Grant Award:
No

PBS Program Name:
ARC 17/18 Discovery
Grant Program:
Discovery Early Career Researcher Award
Grant Activity:
Stronger together: understanding antibiotic synergy on a molecular level
Purpose:
This project aims to use genomics-based approaches to answer fundamental questions about how antibiotic synergy works. Antibiotic combination therapy presents an opportunity to revive the use of antibiotics in otherwise resistant bacteria, yet currently there is little understanding of the molecular mechanisms underlying antibiotic synergy. Studies indicate that additional mechanisms of action (MOA) occur during synergistic killing beyond those of the original antibiotics. This project will identify genes involved in multiple synergistic treatments and determine how bacterial cells gain resistance. The synergy-specific MOA identified also represent an untapped reservoir of primary drug targets.

Internal Reference ID:
DE18 Round 1
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
No
Confidentiality - Outputs:
No

Grant Recipient Details

Recipient Name:
Macquarie University
Recipient ABN:
90 952 801 237

Grant Recipient Location

Suburb:
MACQUARIE PARK
Town/City:
MACQUARIE PARK
Postcode:
2113
State/Territory:
NSW
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
NSW
Postcode:
2113
Country:
AUSTRALIA

Contact Details

ARC NCGP General Enquiries

Phone:
02 6281 6600

Email Address: