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Grant Award View - GA89327
A randomised control trial in subjects with early Alzheimer's disease in...
GA ID:
GA89327
Agency:
Department of Health and Aged Care
Approval Date:
25-May-2020
Publish Date:
29-Jun-2020
Category:
Health and Medical Research
Grant Term:
1-Jun-2020 to 31-May-2024
Value (AUD):
$1,720,000.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
DoHAC 19/20 1.1 Health Policy Research and Analysis
Grant Program:
2019_MRFF_RCRDUN_Neurological_Disorders_2020
Grant Activity:
A randomised control trial in subjects with early Alzheimer's disease in exploring if probucol supports cognitive function through improved cerebrovascular function
Purpose:
We have identified that leakage from blood-into-brain of fat/protein complexes can trigger Alzheimer’s disease (AD). Moreover, we have also identified an historic drug that inhibits the production and leakage into brain of these toxic fat/protein moieties. The drug of interest is well tolerated and has an excellent safety profile, providing rapid translational opportunities. This study may provide a completely new treatment opportunity for patients with AD.
GO ID:
GO Title:
MRFF Clinical Trials Activity - RCRDUN Initiative – 2019 Neurological Disorders Grant Opportunity
Internal Reference ID:
MRF1201204
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Curtin University
Recipient ABN:
99 143 842 569
Grant Recipient Location
Suburb:
Bentley
Town/City:
Bentley
Postcode:
6102
State/Territory:
WA
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
WA
Postcode:
Country:
AUSTRALIA