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Grant Award View - GA68586
Understanding how an old heart gets stiff
GA ID:
GA68586
Agency:
Australian Research Council
Approval Date:
20-Dec-2019
Publish Date:
6-Jan-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
28-Feb-2020 to 27-Feb-2023
Original: 1-Jan-2020 to 31-Dec-2022
Value (AUD):
$440,000.00
(GST inclusive where applicable)
Variations:
- GA68586-V3 - Variation to Grant (20-Oct-2021 )
- GA68586-V2 - Variation to Grant (2-Aug-2021 )
- GA68586-V1 - Variation to Grant (5-May-2020 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Understanding how an old heart gets stiff
Purpose:
Aging is accompanied by a stiffening of the heart and reduced function, which is accelerated by cardiovascular disease and leads to heart failure. How the heart stiffens is poorly understood. A new mechanism is proposed here, involving structural membrane proteins (termed caveolae and cavins) and a signalling molecule (nitric oxide). The current research aims to unravel the interplay between cardiac cells and these proteins/signals to cause stiffness and to determine whether this process governs normal aging of the heart. This work will advance understanding of how heart function is determined and reveal how the human heart changes with normal aging.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Queensland
Recipient ABN:
63 942 912 684
Grant Recipient Location
Suburb:
ST LUCIA
Town/City:
ST LUCIA
Postcode:
4067
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
QLD
Postcode:
4067
Country:
AUSTRALIA