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Grant Award View - GA68520
Peril and promise: Origins and spread of integron gene cassettes
GA ID:
GA68520
Agency:
Australian Research Council
Approval Date:
19-Dec-2019
Publish Date:
6-Jan-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
13-Nov-2020 to 12-Nov-2024
Original: 1-Jan-2020 to 31-Dec-2022
Value (AUD):
$530,000.00
(GST inclusive where applicable)
Variations:
- GA68520-V4 - Variation to Grant (3-Apr-2024 )
- GA68520-V3 - Variation to Grant (20-Oct-2021 )
- GA68520-V2 - Variation to Grant (2-Aug-2021 )
- GA68520-V1 - Variation to Grant (1-Jun-2021 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Peril and promise: Origins and spread of integron gene cassettes
Purpose:
Integrons have a major role in spreading antibiotic resistance genes among pathogens. They do so by capturing gene cassettes encoding resistance, yet how these cassettes are generated, the taxa in which they originate, and the range of traits that cassettes can encode have been outstanding questions for 30 years. This project addresses these long standing questions. The project will analyze single bacterial cells to detect newly generated cassettes and assign them to specific taxa, using an innovative method that links cassette DNA to bacterial 16S rDNA. Understanding cassette origins is the key to controlling their activity, both to harness integrons for biotechnology, and to prevent pathogens from acquiring new, dangerous traits.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Macquarie University
Recipient ABN:
90 952 801 237
Grant Recipient Location
Suburb:
MACQUARIE UNIVERSITY
Town/City:
MACQUARIE UNIVERSITY
Postcode:
2109
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2109
Country:
AUSTRALIA