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Grant Award View - GA68416
Sphingosine-1-phosphate receptor 5: a novel regulator of T cell immunity
GA ID:
GA68416
Agency:
Australian Research Council
Approval Date:
20-Dec-2019
Publish Date:
6-Jan-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jan-2020 to 31-Dec-2022
Value (AUD):
$560,500.00
(GST inclusive where applicable)
Variations:
- GA68416-V2 - Variation to Grant (20-Oct-2021 )
- GA68416-V1 - Variation to Grant (2-Aug-2021 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Sphingosine-1-phosphate receptor 5: a novel regulator of T cell immunity
Purpose:
T cells provide critical immune protection against infection and cancer. However, the pathways that regulate these immune cells are not fully understood. T cells express a molecule called S1P5 that has an unknown function in these cells. In this proposal, we reveal new evidence that this molecule is an unappreciated and crucial regulator of T cell behaviour. Using state-of-the-art techniques and novel genetic tools, this project aims to discover the involvement of S1P5 in the immune response, and determine how S1P5 can be controlled to enhance protective T cell immunity. The expected outcomes are to generate fundamental new knowledge that will have significance for regulation of the immune response.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
UNIVERSITY OF MELBOURNE
Town/City:
UNIVERSITY OF MELBOURNE
Postcode:
3010
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3010
Country:
AUSTRALIA