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Grant Award View - GA29060
How the red blood cell loses its nucleus
GA ID:
GA29060
Agency:
Australian Research Council
Approval Date:
27-Nov-2018
Publish Date:
18-Dec-2018
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Sep-2019 to 31-Dec-2023
Original: 1-Jan-2019 to 31-Dec-2021
Value (AUD):
$507,000.00
(GST inclusive where applicable)
Variations:
- GA29060-V4 - Variation to Grant (17-May-2023 )
- GA29060-V3 - Variation to Grant (20-Oct-2021 )
- GA29060-V2 - Variation to Grant (2-Aug-2021 )
- GA29060-V1 - Variation to Grant (9-Jul-2019 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 18/19 Discovery
Grant Program:
Discovery Projects
Grant Activity:
How the red blood cell loses its nucleus
Purpose:
This project aims to provide insights into erythroid enucleation, the process by which red blood cells extrude their nucleus so that they can circulate through the microvasculature. Although the enucleated character of mammalian red blood cells has been known for more than 150 years, the mechanism underlying this process is virtually unknown. This project will use a live imaging approach to characterise in vivo the cellular interactions and molecular pathways required for enucleation. The project will provide a molecular and cellular road map of enucleation that may be utilised to enhance the bulk therapeutic in vitro production of red blood cells for veterinary and human purposes.
GO ID:
GO Title:
Discovery Projects commencing in 2019
Internal Reference ID:
DP19 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
La Trobe University
Recipient ABN:
64 804 735 113
Grant Recipient Location
Suburb:
BUNDOORA
Town/City:
BUNDOORA
Postcode:
3086
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3086
Country:
AUSTRALIA