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Grant Award View - GA28630
Molybdenum enzyme electrochemical communication
GA ID:
GA28630
Agency:
Australian Research Council
Approval Date:
27-Nov-2018
Publish Date:
18-Dec-2018
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Feb-2019 to 30-Jun-2022
Original: 1-Jan-2019 to 31-Dec-2021
Value (AUD):
$351,142.00
(GST inclusive where applicable)
Variations:
- GA28630-V4 - Variation to Grant (21-Jun-2022 )
- GA28630-V3 - Variation to Grant (20-Oct-2021 )
- GA28630-V2 - Variation to Grant (2-Aug-2021 )
- GA28630-V1 - Variation to Grant (16-Jul-2019 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 18/19 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Molybdenum enzyme electrochemical communication
Purpose:
This project aims to understand the activity of three novel, but related, molybdenum enzymes, human mARC and its bacterial homologs YcbX and YiiM. The role of mARC in humans remains unknown twelve years after its discovery. All three enzymes catalyse the reduction of potentially harmful N-hydroxylated compounds and there is interest in this area from the perspective of drug design. This project will apply an electrochemical methodology to rapidly identify enzyme substrates and inhibitors. Molybdenum enzymes pervade all life forms and the outcomes of this research include a unified understanding of an emerging enzyme class involved in drug metabolism.
GO ID:
GO Title:
Discovery Projects commencing in 2019
Internal Reference ID:
DP19 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Queensland
Recipient ABN:
63 942 912 684
Grant Recipient Location
Suburb:
ST LUCIA
Town/City:
ST LUCIA
Postcode:
4067
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
QLD
Postcode:
4067
Country:
AUSTRALIA