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Grant Award View - GA28573

Elucidating a novel mechanism for coping with harmful mutations

Contact Details

ARC NCGP General Enquiries

Phone:
02 6281 6600

Email Address:

GA ID:
GA28573
Agency:
Australian Research Council
Approval Date:
27-Nov-2018
Publish Date:
18-Dec-2018
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Feb-2019 to 31-Jan-2022
Original: 1-Jan-2019 to 31-Dec-2021
Value (AUD):
$414,864.00 (GST inclusive where applicable)
Variations:

Ad hoc/One-off:
No
Aggregate Grant Award:
No

PBS Program Name:
ARC 18/19 Discovery
Grant Program:
Discovery Early Career Researcher Award
Grant Activity:
Elucidating a novel mechanism for coping with harmful mutations
Purpose:
This project aims to improve our understanding of the complex regulatory mechanisms that increase genetic and phenotypic robustness. Survival of organisms depends on their ability to cope with genetic variation. A novel process of genetic compensation has recently been identified, producing a normal phenotype in a homozygous mutant, that would be expected to have deleterious effects. This project will reveal how compensation is achieved by examining the molecular pathways that are activated following genetic mutation. This project is expected to strengthen Australian reputation in evolutionary genetics, and in turn enhance our understanding of how organisms adapt to changing environments.

Internal Reference ID:
DE19 Round 1
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
No
Confidentiality - Outputs:
No

Grant Recipient Details

Recipient Name:
Monash University
Recipient ABN:
12 377 614 012

Grant Recipient Location

Suburb:
CLAYTON
Town/City:
CLAYTON
Postcode:
3168
State/Territory:
VIC
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
VIC
Postcode:
3168
Country:
AUSTRALIA

Contact Details

ARC NCGP General Enquiries

Phone:
02 6281 6600

Email Address: