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Grant Award View - GA28488
Studying early human kidney development using stem cells
GA ID:
GA28488
Agency:
Australian Research Council
Approval Date:
27-Nov-2018
Publish Date:
18-Dec-2018
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
14-Jun-2019 to 13-Jun-2022
Original: 1-Jan-2019 to 31-Dec-2021
Value (AUD):
$437,000.00
(GST inclusive where applicable)
Variations:
- GA28488-V3 - Variation to Grant (20-Oct-2021 )
- GA28488-V2 - Variation to Grant (2-Aug-2021 )
- GA28488-V1 - Variation to Grant (2-Jun-2020 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 18/19 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Studying early human kidney development using stem cells
Purpose:
This project aims to improve our understanding of cell types, lineage relationships, cell-cell interactions and morphogenetic processes in human kidney development. Investigators have developed a method to produce multicellular kidney organoids from human pluripotent stem cells (hPSC). This project will use gene-edited reporter hPSC lines and high-res imaging to study the lineage relationships and morphogenetic mechanisms of these human kidney organoids. This project aims to validate the origin of nephrons in kidney organoids, study the origin of the renal stroma versus the nephron progenitor, and monitor nephron patterning and segmentation at a clonal level. This will improve our knowledge of human kidney development in a human model.
GO ID:
GO Title:
Discovery Projects commencing in 2019
Internal Reference ID:
DP19 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
UNIVERSITY OF MELBOURNE
Town/City:
UNIVERSITY OF MELBOURNE
Postcode:
3010
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3010
Country:
AUSTRALIA