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Grant Award View - GA28473-V1
Radical redox indicators
GA ID:
GA28473-V1
Agency:
Australian Research Council
Approval Date:
27-Nov-2018
Variation Publish Date:
9-Jul-2019
Variation Date:
9-Jul-2019
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jun-2019 to 31-May-2022
Value (AUD):
$400,000.00
(GST inclusive where applicable)
Varies:
GA28473
- Radical redox indicators
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 18/19 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Radical redox indicators
Purpose:
This project aims to synthesise the first examples of advanced biological imaging agents that can reversibly respond to the oxidative status of living cells. Novel mitochondrially-targeted, fluorescent probes will be derived from several well-established families of biological dyes through the introduction of a stable free radical within the parent structure. The design of the new imaging agents aims to both enhance retention in, and restrict the fluorescence response to, the mitochondria so that changes in oxidation and reduction can be monitored. The probes will provide an innovative new means to assess reactive species and associated oxidative stress, thus delivering a new methodology to aid research into mitochondrial chemical biology.
GO ID:
GO Title:
Discovery Projects commencing in 2019
Internal Reference ID:
DP19 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Queensland University of Technology
Recipient ABN:
83 791 724 622
Grant Recipient Location
Suburb:
BRISBANE CITY
Town/City:
BRISBANE CITY
Postcode:
4000
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
QLD
Postcode:
4000
Country:
AUSTRALIA