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Grant Award View - GA68502-V1
Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches
GA ID:
GA68502-V1
Agency:
Australian Research Council
Approval Date:
19-Dec-2019
Variation Publish Date:
7-Feb-2020
Variation Date:
15-Jun-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
15-Jun-2020 to 14-Jun-2023
Value (AUD):
$469,000.00
(GST inclusive where applicable)
Varies:
GA68502
- Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches
Purpose:
Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
FOREST LODGE
Town/City:
FOREST LODGE
Postcode:
2037
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2037
Country:
AUSTRALIA