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Grant Award View - GA30193

Silencing silencers to boost foetal globin production and treat...

Contact Details

NHMRC Research Help Centre

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1800 500 983

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GA ID:
GA30193
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
21-Dec-2018
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2021
Value (AUD):
$560,394.00 (GST inclusive where applicable)

One-off/Ad hoc:
No
Aggregate Grant Award:
No

PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Silencing silencers to boost foetal globin production and treat ?-haemoglobinopathies
Purpose:

The genetic disorders ?-thalassaemia and sickle cell anaemia are caused by mutations in the adult globin gene. Fortunately, humans have a second globin gene, the foetal ?-globin gene, which is expressed in utero but turned off after birth. Re-activating expression of this foetal globin gene can alleviate the symptoms of ?-thalassaemia and sickle cell anaemia. We are using cutting edge gene editing technology to explore strategies for boosting foetal globin expression in affected individuals.


GO ID:
GO Title:
NHMRC Project Grant Scheme
Internal Reference ID:
GNT1164920
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property

Grant Recipient Details

Recipient Name:
University of New South Wales
Recipient ABN:
57 195 873 179

Grant Recipient Location

Suburb:
Sydney
Town/City:
Sydney
Postcode:
2052
State/Territory:
NSW
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
NSW, Overseas
Postcode:
Multiple
Country:
AUSTRALIA, UNITED STATES

Contact Details

NHMRC Research Help Centre

:
1800 500 983

: