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Grant Award View - GA29866
Signal integration of chimeric antigen receptors and the inhibitory...
GA ID:
GA29866
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
21-Dec-2018
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2021
Value (AUD):
$486,811.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Signal integration of chimeric antigen receptors and the inhibitory Programmed cell death protein 1 receptor
Purpose:
T cells recognise and kill infected or cancerous cells and tolerate healthy tissue by integrating information from activating and inhibitory surface receptors. Activating receptors engineered to target cancer show great promise as therapies but their sensitivity to endogenous inhibitory receptors, which cancers exploit, is unknown. We will use powerful biochemical and microscopy techniques to probe this question. The results will inform the design of more effective anti-cancer therapeutics.
GO ID:
GO Title:
NHMRC Project Grant Scheme
Internal Reference ID:
GNT1163814
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of New South Wales
Recipient ABN:
57 195 873 179
Grant Recipient Location
Suburb:
Sydney
Town/City:
Sydney
Postcode:
2052
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW, Overseas
Postcode:
Multiple
Country:
AUSTRALIA, UNITED KINGDOM